Anti-NXP2 dermatomyositis: initial enlarged loops

Prominent enlarged loops and a complex branching form in the initial anti-NXP2 dermatomyositis study. Compare this with the linked follow-up image and complete serial studies.

Prominent enlarged loops and a complex branching form in the initial anti-NXP2 dermatomyositis study. Compare this with the linked follow-up image and complete serial studies.
Prominent enlarged loops and a complex branching form in the initial anti-NXP2 dermatomyositis study. Compare this with the linked follow-up image and complete serial studies.

Source study context

The first study shows an active scleroderma/myositis-like microangiopathy with severe capillary loss, giant capillaries, arborizing ramifications, hemorrhages, architectural disorganization, and avascular areas. The follow-up study shows regression to a non-specific pattern with improved density and disappearance of giant capillaries and hemorrhages.

Measurements and classification refer to the described study or visit; they are not new measurements of this image.

View the complete case and study

Image details

Pathology
Dermatomyositis (anti-NXP2+)
Pattern
Myositis-Associated Microangiopathy with Treatment Response
Author or contributor
Luis Saez Comet
Hallmarks
Giant capillaryCapillary density
Magnification
250×
Device
Smart G-Scope
Field of view (W × H)
≈ 2.30 × 1.29 mm
Open full-size image

Teaching point

Describe whether abnormalities are isolated, repeated, or combined.

Clinical caveat

This image illustrates a visual finding and should be interpreted with acquisition quality, distribution across fingers, clinical context, and serology when relevant.

Use and licensing

Contributed by Luis Saez Comet for educational publication on Capillaroscopy.com. For reuse permissions, contact the rights holder.

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