Anti-U3 RNP systemic sclerosis: irregular loops

Irregular enlarged loops in the anti-U3 RNP case. Although giants remain present, the final report classifies the overall microangiopathy as late.

Irregular enlarged loops in the anti-U3 RNP case. Although giants remain present, the final report classifies the overall microangiopathy as late.
Irregular enlarged loops in the anti-U3 RNP case. Although giants remain present, the final report classifies the overall microangiopathy as late.

Source study context

There is marked capillary loss (4.9/mm), architectural disorganization, frequent dilations, giant capillaries in 14.9% of capillaries, and abnormal or ramified forms. This pattern was classified by the CAPI-Detect algorithm as active; however, due to the frequent features characteristic of late-stage involvement, it was ultimately classified as such in the final report.

Measurements and classification refer to the described study or visit; they are not new measurements of this image.

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Image details

Pathology
Systemic Sclerosis (anti-U3 RNP+)
Pattern
Late scleroderma pattern
Author or contributor
Miguel Antonio Mesa Navas
Hallmarks
Late scleroderma pattern
Magnification
250×
Device
Smart G-Scope
Field of view (W × H)
≈ 2.39 × 1.34 mm
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Teaching point

Review several fingers before concluding that density is low or the pattern is abnormal.

Clinical caveat

This image illustrates a visual finding and should be interpreted with acquisition quality, distribution across fingers, clinical context, and serology when relevant.

Use and licensing

Contributed by Miguel Antonio Mesa Navas for educational publication on Capillaroscopy.com. For reuse permissions, contact the rights holder.

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